Serous membrane

Serous Membrane
Layers of the enteric nervous system. (Serosa at top, in red.)
Stomach. (Serosa is labeled at far right, and is colored yellow.)
Latin tunica serosa
System Micah Goodson
Precursor mesoderm
MeSH Serous+membrane

In anatomy, serous membrane (or serosa) is a smooth membrane consisting of a thin layer of cells which secrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them.

Contents

Structure

Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath.

For the heart, the surrounding serous membranes include:

Outer Inner
Parietal pericardium Visceral pericardium (epicardium)

Other parts of the body may also have specific names for these structures. For example, the serosa of the uterus is called the perimetrium.

The pericardial cavity (surrounding the heart), pleural cavity (surrounding the lungs) and peritoneal cavity (surrounding most organs of the abdomen) are the three serous cavities within the human body. While serous membranes have a lubricative role to play in all three cavities, in the pleural cavity it has a greater role to play in the function of breathing.

The serous cavities are formed from the intraembryonic coelom and are basically an empty space within the body surrounded by serous membrane. Early in embryonic life visceral organs develop adjacent to a cavity and invaginate into the bag-like coelom. Therefore each organ becomes surrounded by serous membrane - they do not lie within the serous cavity. The layer in contact with the organ is known as the visceral layer, while the parietal layer is in contact with the body wall.

Embryological origins

All serous membranes found in the human body formed ultimately from the mesoderm of the trilaminar embryo. The trilaminar embryo consists of three relatively flat layers of ectoderm, endoderm (also known as "entoderm") and mesoderm.

As the embryo develops, the mesoderm starts to segment into three main regions: the paraxial mesoderm, the intermediate mesoderm and the lateral plate mesoderm.

The lateral plate mesoderm later splits in half to form two layers bounding a cavity known as the intraembryonic coelom. Individually, each layer is known as splanchnopleure and somatopleure.

The intraembronic coelom can now be seen as a cavity within the body which is covered with serous membrane derived from the splanchnopleure. This cavity is divided and demarcated by the folding and development of the embryo, ultimately forming the serous cavities which house many different organs within the thorax and abdomen.

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